The DMG test performed on her hands 2 hours before work was negative for nickel and the DMG test performed 2 hours after work was positive for nickel. The patient was tested using the DMG test for the presence of nickel. A patch test showed a 3 + reaction (i.e., extreme reaction) to nickel sulfate. The test can also be used on skin after metal contact.Ī case report of a 32-year-old female with a 5-year history of palmar hand eczema due to occupational nickel exposure has been reported. Baumgartner, in Side Effects of Drugs Annual, 2016 Nickel Allergy Leading to Hand Eczema Semi-Quantified with Dimethylglyoxime Testingĭimethylglyoxime (DMG) testing is a semi-quantitative test that gives a positive result when > 0.5 μg Ni/cm 2/week is released from a metallic surface.